Snow White and the Seven Dwarfs

Original theatrical poster from Wikipedia
From the Wikipedia entry:

Snow White and the Seven Dwarfs is a 1937 animated feature, the first produced by Walt Disney. Although it was not the first full-length animated feature to be produced (the 1917 Argentine film El Apóstol holds that distinction, and there are seven other earlier ones), it was the first animated feature to become widely successful within the English-speaking world and the first to be filmed in Technicolor.

The film premiered on December 21, 1937, with a wide theatrical release by RKO Radio Pictures on February 8, 1938.

Snow White was the most successful motion picture released in 1938, and is the tenth highest-grossing film of all time within the United States when adjusted for inflation.

Snow White was one of only two animated films to rank in the American Film Institute's list of the 100 greatest American films of all time in 1997 (the other being Fantasia), ranking #49.

In 1989, Snow White and the Seven Dwarfs was added to the United States National Film Registry as being deemed "culturally, historically, or aesthetically significant."

Adjusted for inflation, the film is the highest grossing animated film.